Giant Fungating Cutaneous Myxoma of the Head and Neck: An Unusual Presentation

Main Article Content

Aliyu Daniel
K. R. Iseh
J. H. Solomon
Olawole W. Olalekan
Braimah R. Oyebunmi
Ibikunle A. Aremu
Taiwo A. Olanrewaju
Sahabi S. Mallami
Adeyeye M. Folusho
Nazish P. Aquil
S. B. Amutta
M. Abdullahi
Okoro C. Joshua

Abstract

Introduction: Virchow first describes Myxomas in 1871; they are benign tumors of primitive indifferent mesenchyme that have preference for the cardiac muscles, genitourinary tract, gastrointestinal tract, liver and spleen. The rarity of the tumor, especially in the head and neck region makes us to report this case.

Case Report: A 16-year-old male secondary student who presented with a 9-year history of painless progressive submandibular swelling, no extension to the mouth. Examination revealed a huge fungating submandibular mass, 20 cm x 16 cm x10 cm in dimension, mobile, non-tender and firm in consistency. Other findings were unremarkable, and routine hematological and biochemical tests were all within normal limits. He subsequently had excision of the mass (weighs 950 g) under general anesthesia via an elective tracheostomy with split thickness skin grafting of the exposed strap muscles. Histopathological report revealed cutaneous myxoma.

Conclusion: Cutaneous myxoma of the Head and Neck region is presented for its rarity, and although is a histologically benign neoplasm, treatment is extremely challenging with high incidence of recurrence.

Keywords:
Cutaneous myxoma, head and neck, benign, submandibular

Article Details

How to Cite
Daniel, A., Iseh, K. R., Solomon, J. H., Olalekan, O. W., Oyebunmi, B. R., Aremu, I. A., Olanrewaju, T. A., Mallami, S. S., Folusho, A. M., Aquil, N. P., Amutta, S. B., Abdullahi, M., & Joshua, O. C. (2019). Giant Fungating Cutaneous Myxoma of the Head and Neck: An Unusual Presentation. Journal of Cancer and Tumor International, 9(4), 1-5. https://doi.org/10.9734/jcti/2019/v9i430112
Section
Case study

References

Batsakis JG. Myxomas of soft tissues and the facial skeleton. Ann Otol Rhinol Laryngol. 1987;96:618-619.

Ireland DCR, Soule EH, Ivins JC. Myxoma of somatic soft tissues. Mayo Clin Proc. 1973;48:401-410.

Canalis RF, Smith GA, Konrad HR. Myxomas of the head and neck. Arch Otolaryngol. 1976;102:300-305.

Stout AP. Myxoma tumor of primitive mesenchyme. Ann Surg. 1948;127:706-719.

Andrews T, Kountakisse, Maillard AA. Myxomas of the head and neck. Am J Otolariyngol. 2000;21:184-9.

Virchow R. Die cellularpathologie in ihrer Beegrundung auf physiologische and pathologische Gewebelehre. Berlin, Germany, Verlag von August Hirschwald. 1871;563.

Galera-Ruiz H, Martin-Gomez R, Esteban-Ortega F, Congregado-Loscertales M, Garcia Escudero A. Extramuscular soft-tissue myxoma of the lateral neck. Rev Laryngol Otol Rhinol. 2001;122:259-61.

Carney JA, Gordon H, Carpenter PC, Shenoy BV, Go VL. The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine (Baltimore). 1985;64:270-83.

Casey M, Vaughan CJ, He J, Hatcher CJ, Winter JM, Weremowicz S, et al. Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex. J Clin Invest. 2000; 106:R31-8.

Enziger FM. Intramuscular myxoma. Am J Chin Pathol. 1965;43:104-13.

Ghosh BC, Huvos AG, Gerald FP, et al. Myxoma of the jawbones. Cancer. 1973; 3:237-40.

Ireland DC, Soule E, Ivins J: Myxoma of somatice soft tumors-A report of 58 patients, 3 with multiple tumors and fibrous dysplasia of bone. Mayo Clinic Pro. 1973; 48:401.

Allen PW. Myxoma is not a single entity: A review of the concept of myxoma. Ann Diagn Pathol. 2000;4:99-123.

Zimmerman DC, Dahlin DC. Myxomatous tumors of the jaws. Oral Surg Oral Med Oral Pathol. 1958;11:1069-1080.

Shuman R, Anderson W: Mesenchymal tumors of soft tis-soft tissue myxorna sue, in anderson (eds): Pathology (ed 7). St. Louis, CV Mosby. 1977; 1887.

Tomich CE: Oral focal mucinosis: A clinicopathological and histochemical study of eight cases. Oral Surg. 1974; 38:714.

Cook CA, Lund BA, Carney JA. Mucocutaneous pigmented spots and oral myxomas: The oral manifestations of the complex of myxomas, spotty pigmentation and endocrine overactivity. Oral Surg Oral Med Oral Pathol. 1987;63:175-183.

Carney JA, Hruska LS, Beauchamp GD, Gordon H. Dominant inheritance of the complex of myxomas, spotty pigmentation, and endocrine overactivity. Mayo Clin Proc. 1986;61:165-172.

Ken I, Takeshi E, Masato S, Yusuke S, Hirotsugu O. Cutaneous Myxoma of Multiple Lesions. Plast Reconstr Surg Glob Open. 2019;7:e2040.

Barbach Y, Mazti A, Baybay H, Chaouche M, Cherif AD, Hamas N, et al. Solitary cutaneous myxoma in a child: Rare entity. Int J Pediat Health Care Adr. 2018;5(5):92-94.

Yehia S, Basma H, Abdallah A, Ola A, Mohamed S, Mahmoud A, et al. Carney complex: A rare case of multicentric cardiac myxoma associated with endocrinopathy. Case Reports in Cardiology. 2018;1-7.

Zimmerman DC, Dahlin DC: Myxomatous tumors of the jaws. Oral Surg. 1958; 11:1069-1080.

Killey HC, Kay LW: Fibromyxomata of the jaws. BrJ Oral Surg. 1964;2: 124.